These instructions were tested with Adobe Photoshop CS5.1 (the 30-day trial from Adobe's website) under Ubuntu 11.10 using WINE 1.4-rc5. I was not able to get the installer to work, however the method of installing on Windows and then copying over did work (see this guide). The directories I copied were:
C:\Program Files\Adobe\
C:\Program Files\Common Files\Adobe
C:\Program Files (x86)\Adobe
C:\Program Files (x86)\Common Files\Adobe
C:\Users\All Users\Application Data\Adobe\CS5

Note: you must copy each “Program Files” and “Program Files (x86)” folder into the corresponding winebottle folders. I also exported the HKEY_LOCAL_MACHINE/SOFTWARE/Adobe registry tree (using regedit), saving it as adobe.reg. After copying the folders, perform the following additional steps:

Import the registry keys:

Install the following Windows dependencies using winetricks:

Install Adobe Application Manager for activating/managing the trial.

You should now be able to launch Photoshop using the following command: